Boston College Eagles at Florida State Seminoles (-21.5, 45.5)
Why Boston College will cover: A 20-point favorite or more, like Florida State, is only 2-14 ATS in October BCS conference games since the start of the 2009 season.
Why Florida State will cover: Boston College (0-5 ATS) has averaged only 10 points and 264 yards its last three games and face perhaps the most-improved defense in the nation.
Total: Boston College will be fortunate to score in double digits while Florida State may have a hard time running the football against the fifth-best run defense in the FBS.
Illinois Fighting Illini at Michigan State Spartans (-7, 51)
Why Illinois will cover: Since 2006, the Illini are 10-1 ATS as a road underdog.
Why Michigan State will cover: The Spartans (4-2 ATS) desperately want to prove they are the Big Ten?s best. Playing at home, a cover is certainly attainable if laying seven points or less.
Total: The point total could very well be much lower than expected. Illinois struggles in its passing game while Michigan State, coming off a huge victory, might have its offensive troubles as well.
Missouri Tigers vs. Texas A&M Aggies (-3.5, 55.5)
Why Missouri will cover: If QB Blaine Gabbert is healthy, the Tigers should be able to expose a sub-par Texas A&M pass defense (84th in FBS). Following its loss last week, the Aggies are a rather beat up squad.
Why Texas A&M will cover: There is line value as Missouri has yet to be tested this season, having played all of its games in Missouri and against poor-to-average teams.
Total: Based on both teams? reputations, you?d probably predict a shootout. However, Texas A&M is surprisingly seventh in the FBS in rush defense while Missouri is third in scoring defense and seventh in pass efficiency defense.
Mississippi State Bulldogs at Florida Gators (-7.5, 47)
Why Mississippi State will cover: The Bulldogs are improving each week and, as evident by their cover against Florida last year, Dan Mullen is very familiar with his previous coaching stop.
Why Florida will cover: It?s difficult to imagine an Urban Meyer-coached team having three consecutive lackluster performances, especially two in a row at The Swamp.
Total: The Over is both 4-1 in the Gators last five homes games and last five games overall.
South Carolina Gamecocks at Kentucky Wildcats (+4.5, 54.5)
Why South Carolina will cover: The Gamecocks realize how much this game means to their SEC East title chances, plus they never have a hard time with Kentucky, winning 10 in a row, including 6-1 ATS their last seven games against the Wildcats..
Why Kentucky will cover: The Wildcats are perhaps the best non-winning team in college football and betting against them at home, getting points, is a gamble in itself.
Total: Kentucky?s last five games have all gone Over while South Carolina is next to last in the SEC in both passing efficiency defense and total defense.
Mississippi Rebels at Alabama Crimson Tide (-20.5, 55)
Why Mississippi will cover: Give coach Houston Nutt a week to prepare, in an underdog role, against a team that might be searching for some leadership, and a cover is probable.
Why Alabama will cover: The Crimson Tide have been near flawless when playing at home, winning five in a row ATS.
Total: Ole Miss? defense has been more inopportune than deficient, allowing just 362 yards compared to 33 points per game. Despite last week, Alabama still has one of the best defenses in the country.
Iowa Hawkeyes vs. Michigan Wolverines (+3, 53.5)
Why Iowa will cover: Ranking 18th in the nation in turnover margin, the Hawkeyes should be able to force Michigan QB Denard Robinson in committing similar mistakes he did a week ago.
Why Michigan will cover: The underdog is remarkably 8-1 ATS in the last nine games of this series.
Total: Despite Iowa?s stellar defense, no total amount is safe when Michigan?s defense is featured. It?s allowing 27 points and 451 yards per game.
Oklahoma State Cowboys at Texas Tech Red Raiders (-3.5, 69)
Why Oklahoma State will cover: The Cowboys are undefeated and arguably one of the hottest teams in the nation, covering four of their five games this season by an average of 16 points.
Why Texas Tech will cover: The value of the Red Raiders playing at home is often overlooked even though they?ve won 61 percent of their games ATS in Lubbock since 2002.
Total: Both teams average more than 400 yards of offense while also allowing more than 400 yards on defense. Oklahoma State has one of the worst pass defenses in the FBS.
Texas Longhorns at Nebraska Cornhuskers (-9.5, 46.5)
Why Texas will cover: The Longhorns, especially struggling QB Garrett Gilbert, have the advantage coming off a bye week to face a Nebraska squad who has yet to play a top-notch opponent.
Why Nebraska will cover: Texas is one of the worst in the country in turnover margin (-1.00) while the Cornhuskers have scored three touchdowns on turnovers.
Total: Lost in the fact that Texas is having a disappointing season is that the Longhorns defense is very good, ranking first in the Big 12 in total defense and sacks.
Brigham Young Cougars at TCU Horned Frogs (-29, 48.5)
Why BYU will cover: Maybe the Cougars? one glimmer of hope is that they looked impressive in their last game (24-21 over San Diego State) as a decided underdog. Perhaps BYU is amidst a turnaround after a slow start.
Why TCU will cover: The Horned Frogs? rushing attack averages nearly six yards per carry while BYU?s horrid run defense allows 5.1 per rush.
Total: The Under is 6-0 in BYU?s last six games overall and 9-1-2 in TCU?s last 12 games in October.
Utah Utes at Wyoming Cowboys (+20.5, 53)
Why Utah will cover: Wyoming?s current minus-18.3 scoring margin is nearly the same amount of this game?s spread while the Utes have a whopping plus-34.4 margin.
Why Wyoming will cover: The Cowboys play well when established as the underdog, covering 10 of their last 14 games in the dog role.
Total: Any points in this game might be scored by only Utah as Wyoming has one of the worst offenses in college football. The Cowboys rank 118th or worse in the FBS in rushing, scoring and total offense.
Iowa State Cyclones at Oklahoma Sooners (-23.5, 58)
Why Iowa State will cover: Recently, the Sooners have disappointed when a decided favorite, losing their last four games ATS when favored by 10 points or more.
Why Oklahoma will cover: The Sooners? shabby defense allows 4.4 yards per rush. However, Iowa State leading rusher Alexander Robinson, the Cyclones? only reliable offensive weapon, is doubtful for the game.
Total: Considering Robinson likely won?t play, Oklahoma struggles to run the ball (2.8 yards per rush) and the under is 10-3 in Iowa State?s last 13 overall and 13-6 in the Sooners last 19.
Ohio State Buckeyes at Wisconsin Badgers (+3.5, 49)
Why Ohio State will cover: Wisconsin?s defense is slow afoot and will have a difficult time keeping up with QB Terrelle Pryor, who is 18-5 ATS in his last 23 starts.
Why Wisconsin will cover: Camp Randall Stadium, where the Badgers are 7-3 ATS as an underdog since 2001, will greet Ohio State with a rocking and hostile environment.
Total: Ohio State ranks among the Top 6 in four major defensive categories nationally, while Buckeye games have gone under eight consecutive times.
Arkansas Razorbacks at Auburn Tigers (-4, 60.5)
Why Arkansas will cover: The Razorbacks, who could possibly be the best team in the SEC, cannot afford to lose anymore conference games if they want to win the SEC West.
Why Auburn will cover: Since coach Gene Chizik arrived at Auburn, the Tigers are an impressive 10-2 SU and 7-4 ATS at home.
Total: Granted, these two offenses are explosive. However, both teams? defenses have combined to allow just 23 points per game against BCS opponents while steadily improving since the start of the season.
Arizona Wildcats at Washington State Cougars (+23.5, 62)
Why Arizona will cover: The Wildcats have an overwhelming mismatch in their passing game. Arizona ranks 18th in the country in passing efficiency while WSU is 113th in passing-efficiency defense.
Why Washington State will cover: The Cougars are capable of putting some points on the board and could catch Arizona looking ahead to Washington next week.
Total: The Over is 4-1 in both Washington State?s last five games as an underdog and the Cougars? last five home games in this series.
Air Force Falcons at San Diego State Aztecs (+1.5, 53.5)
Why Air Force will cover: In setting the line so low, oddsmakers likely factored in the Falcons? big game at TCU next week. Coach Troy Calhoun?s team is too disciplined to be looking ahead.
Why San Diego State will cover: Last week was the Aztecs first ATS loss in six games. Look for them to bounce back as a home dog.
Total: San Diego?s unsung defense, which allows less than 16 points per game and 3.5 yards per rush, could challenge Air Force?s run-oriented offensive attack.
Boise State Broncos at San Jose State Spartans (+39.5, 56)
Why Boise State will cover: As the Broncos aren?t nationally ranked in the top two spots, they?ll continue to try to impress the voters and likely cover (4-1 ATS this season).
Why San Jose State will cover: The Spartans have recently thrived as a big underdog at home, going 4-1 ATS at Spartan Stadium when an underdog of more than 10 points.
Total: The over is 4-1 in Boise State?s games this season. The Broncos could very easily surpass the total themselves as they?ve scored 50-plus points in three of the last four games.
Nevada Wolf Pack at Hawaii Warriors (+7, 74)
Why Nevada will cover: The Wolf Pack run the ball and Hawaii struggles to stop. The Warriors have the 85th-ranked run defense in the FBS.
Why Hawaii will cover: The Warriors, who usually have a decided home-field advantage over most teams, have covered 60 percent of their home games as an underdog since 2000.
Total: Simply put, while both of these teams? defenses are well below average, both offenses seemingly score every time they touch the ball. There?s little to suggest to play the under.