BEGINNING THURSDAY, MAY 15
Houston at Texas (4) 15th, 16th, 17th, 18th
The Rangers enter the series having won five in a row (+$410 last 10 days), with the 3rd best team ERA in the AL (3.28). The Astros are only 2-7 vs. right-handers on the road in night games (-$670, 1.9 runs per game). Texas, on the other hand, is 12-5 vs. righties at home. Jacob deGrom has stayed healthy through his first eight starts (2.72 ERA), Nathan Eovaldi has a stellar 1.78 ERA in nine outings, while Tyler Mahle’s ERA has been even better (1.47 ERA in nine appearances). All three will be facing right-handers in scheduled evening contests. BEST BET: deGrom/Eovaldi/Mahle.
BEGINNING FRIDAY, MAY 16
Pittsburgh at Philadelphia (3) 16th, 17th, 18th
The Phillies managed to lose money vs. the Pirates in 2024 (-$400) and the Bucs may prove to be an obstacle for the home team this weekend at Citizens Bank. The Phillies are only 3-7 vs. left-handers so far (-$715) and they will have to contend with veteran southpaw Andrew Heaney in the series opener. He has posted a 3.15 ERA in his eight starts, yet he figures to be a hefty road underdog when he takes the mound. BEST BET: Heaney.
Colorado at Arizona (3) 16th, 17th, 18th
The Rockies have been a nightmare up to this point (7-36, -$2095 overall) and there’s nothing positive to point to. They are only 2-20 in road games. They have the worst team ERA in all of baseball (5.73). They average just 3.2 runs per game on offense. However, Arizona’s pitching has been sub-par (4.71 team ERA, 4th worst in the National League), and prices will just be too inflated to seriously consider the home favorite. BEST BET: None.
Detroit at Toronto (3) 16th, 17th, 18th
The 29-15 Tigers have compiled the best record in the American League,and their team stats are among the best in baseball (3.24 team ERA, .758 OPS). They come into this three game set at Rogers Centre riding another hot streak (8-2, +$585 last 10 days). They managed to take 5 of 7 from Toronto in head to head play last year (+$355) and they’ll be sending a trio of right-handers at the Blue Jays, who are only 3-10 vs. righties in day games (+$765). BEST BET: Right-handers vs. the Blue Jays in day games.
Chicago Cubs at Chicago W. Sox (3) 16th, 17th, 18th
The White Sox are still terrible, but they are better than they were last year, and they are capable of stealing a win here at Wrigley Field. They have turned a profit vs. left-handers in 2025 (+$390) and they will be catching a fat underdog price when they face Matthew Boyd on Saturday. Boyd will square off against Sean Burke (+$285 in eight starts), who comes in with a 1.74 ERA in his two most recent appearances. BEST BET: Burke vs. Boyd.
Cleveland at Cincinnati (3) 16th, 17th, 18th
The 25-18 Guardians are off to a strong start in 2025, tied with New York for the 2nd best record in the American League. However, they’ve been a disappointment when facing left-handers (2-5, -$245), averaging just 3.1 runs per game at the plate. The Reds have been sub-par lately (3-7, -$585 last 10 days) but they have Andrew Abbott, one of the NL’s better southpaws, set to take the hill in Sunday’s finale. Abbott enters the game with a 2.10 ERA in his six starts so far. BEST BET: Abbott.
Washington at Baltimore (3) 16th, 17th, 18th
After two solid seasons the Orioles have hit the skids in 2025 (-$1680 overall), and they enter this series having lost 8 of their last 10. They have the worst pitching in the American League (5.34) and they’ve averaged just 3.0 runs per game in their last 10). The Nationals are in a slump as well 2-8, (-$550 last 10 days) and they are only 8-15 on the road so far (-$520). We’ll keep an eye out, but this match-up does not look promising. BEST BET: None.
N.Y. Mets at N.Y. Yankees (3) 16th, 17th, 18th
Two first place New York teams collide in the Bronx this weekend. The Mets are flying high atop the NL East, but they are only a .500 team outside of CitiField (-$290), and while they have the league’s top mound corps, their starters have a somewhat bloated 4.30 in the past 10 days. Max Fried has been the Yankees’ ace through nine starts (+$645, 1.27 ERA). He’ll face fellow southpaw David Peterson in Sunday’s evening finale (Yanks 6.3 runs per game vs. lefties). BEST BET: Fried vs. Peterson.
Atlanta at Boston (3) 16th, 17th, 18th
The Braves are up to .500 following a dreadful start, and they make an appealing choice at Fenway Park. Boston (-$795 overall) comes in having just been swept by the Tigers at Comerica. Atlanta compiled a 31-15 record in inter-league play last year (+$610), while the Red Sox floundered vs. NL teams (-$795). Lucas Giolito has not looked sharp since joining the rotation (4.96 ERA), so grab Atlanta when he goes. BEST BET: Braves vs. Giolito.
Tampa Bay at Miami (3) 16th, 17th, 18th
The Rays have been at their best in road games this year (+$680) and they draw a soft opponent in Miami this weekend. The Marlins continue to flounder in the NL East cellar (2-8, -$260 last 10 days). They have a 5.53 team ERA, and none of the starters they have scheduled to appear looks promising. Tampa Bay should take at least 2 out of 3. BEST BET: Rays in all games.
St. Louis at Kansas City (3) 16th, 17th, 18th
The smoking hot Cardinals finally saw their win streak snapped (10-1, +$1090 last 10 days). They are now within just one game of first place in the NL Central as they get set to visit Kaufman Stadium. However, they’ve performed poorly on the road (only 9-14, -$310), while the Royals have a 16-7 record at home (+$800) to go with the AL’s best overall pitching (3.03 ERA). The match-ups seem to favor the home team, who are likely to come away with 2 out of 3. BEST BET: Royals in all games.
Minnesota at Milwaukee (3) 16th, 17th, 18th
The Twins have won 11 on a row (+$1160), but this looks like a very challenging series for a Minnesota team that was only 18-28 against NL teams in 2024 (-$1930). The Brewers racked up a hefty profit in inter-league play last year (+$1790) and they have a pair of quality right-handers in Chad Patrick (2.83 ERA in eight starts) and Freddy Peralta (2.66) set to take the mound. Milwaukee has a 12-7 record at home (+$430), while the Twins are only 9-14 outside of Target Field (-$520). BEST BET: Patrick/F. Peralta.
Seattle at San Diego (3) 16th, 17th, 18th
The Mariners’ grip on 1st place in the AL West is slipping (3-7, -$535 last 10 days, with a 6.78 ERA among starters) and they now face a daunting task at Petco Park, where the Padres have a stellar 16-5 record so far (+$945). Stephen Kolek (+$200, 0.00 ERA in two starts), Nick Pivetta (3.05) and Michael King (2.33) should fare well against a Seattle club that has lost money vs. right-handers in 2025 (-$615). BEST BET: Kolek/Pivetta/King.
L.A. Angels at L.A. Dodgers (3) 16th, 17th, 18th
The Dodgers are now 17-4 at home (+$865) so they’ll be prohibitively expensive when hosting the last place Angels, who are only 8-15 outside of Anaheim (-$480). Despite these concerns, we are tempted to take Tyler Anderson as a fat underdog here at Chavez Ravine. He checks in with a 2.58 ERA, having led the Angels to wins in 6 of his 8 starts (+$560). Clayton Kershaw is slated to make his first start in 2025 for the Dodgers. BEST BET: T. Anderson.
Oakland at San Francisco (3) 16th, 17th, 18th
The Giants have lost 6 of their last 9 (-$225) and they will have their hands full with the Athletics, who are now 14-9 on the road in 2025 (+$770). The Giants are a pitiful 2-10 vs. left-handers (-$1045, 3.3 runs per game). JP Sears (+$455, 2.80 ERA) and Jeffrey Springs (2.25 ERA last two outings) are hard to pass up as underdogs here at Oracle Park. BEST BET: Sears/Springs.