The Cubs swept a three game set from this team at Petco Park (+$300) and they can extend their tenuous lead in the NL Central with a strong showing in this four game set. Chicago?s rotation was loaded with southpaws before they acquired Cole Hamels, and that is terrible news for a San Diego team that is only 10-22 vs. lefthanders (-$965), while averaging just 2.7 runs per game against them in road games. The Padres have several lefty starters as well, but the Cubs are 18-7 in that situation (+$805), averaging 5.8 runs per game in those contests. BEST BET: Cubs when lefty meets lefty