| Line | Total |
|---|---|
| Kansas City Chiefs at New England Patriots (-7) | 50 |
| New York Jets at Buffalo Bills (-6.5) | 42 |
| Atlanta Falcons (-5.5) at Chicago Bears | 50.5 |
| Jacksonville Jaguars at Houston Texans (-4.5) | 42 |
| Philadelphia Eagles at Washington Redskins (-2.5) | 48 |
| Arizona Cardinals at Detroit Lions (-2.5) | 49.5 |
| Oakland Raiders at Tennessee Titans (PK) | 53.5 |
| Tampa Bay Buccaneers at Miami Dolphins (-2) | 48 |
| Baltimore Ravens at Cincinnati Bengals (-1) | 44 |
| Pittsburgh Steelers (-9.5) at Cleveland Browns | 47.5 |
| Indianapolis Colts (-3.5) at Los Angeles Rams | 48 |
| Seattle Seahawks at Green Bay Packers (-2.5) | 50.5 |
| Carolina Panthers (-4) at San Francisco 49ers | 49 |
| New York Giants at Dallas Cowboys (-6) | 50.5 |
| New Orleans Saints at Minnesota Vikings (-4) | 48 |
| Los Angeles Chargers at Denver Broncos (-3.5) | 44.5 |
<thead>
</thead><tbody class="row-hover">
</tbody>
