It seems to me that you have to do this somewhat blindly. I do agree that I would not want to chase KC at home against the Red Sox. But then again, TB beat Boston last night so Boston did not sweep at home, which you might have thought going in.
I think you do need to look at each series, but for me, if I start trying to decide which teams i think will for sure win one home game, then it isn't a system anymore and it is me picking games.
I think common sense should be the best course of action.
One other thing I have found is that the home team has won one of the first two games a lot of the time. This week so far, none of the chases has gone more than two games. If this trend continues, I think there would be opportunities to pull back and lock in profit. This week for example, when I went to bed Wednesday, I assumed that Seattle had lost again at home to Texas. At that point, the 14 other series for the week were in the bag. I had a profit locked in for certain. Has Seattle lost and I chased game three, I risked losing money for the series, so I planned to just wait for the next group of series to start up and not be greedy.
That being said, the season is very young and we shall see. But the facts are that even the best team in the league will lose 50-60 games this year.