MadJack's Sportsbar

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These are trippy.
Overkill is not just the outback of the Flower Mound.
Throw deep or perish.


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--preview teased that it would embed


--fuck it; the instagram link sorta works; from last week already; minds on the Super Bowl and the gutter might
 
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Nursing #3.
Doesn't mean I have 3 personals, or 1.5 ladies, just a booze reference.
Sparking a Kali Mist to prevent further stupid jokes.
Not a sure thing.


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Not sure if there is a proper social service agency to contact, or some kind of appropriate self-help treatment to seriously delve into, but I am back to abusing my subwoofer, again. Feedback might be due to song selection but the free will joke is overkill.


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Called a friend who talked me out of calling my lawyer.
Good play.


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MDMA is apparently unique in its dual effects on both the serotonergic system and the dopinaminorgic system. Whatever that means. Makes people unhate, if that's a word.


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#past my bedtime
I was asked recently if AC/DC could be classified as "heavy metal."
True story, as they say in sadcamp.

Crucial threshold influence is indeterminate, according to this interview I suffered:
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I was desperate for distraction and the requisite suspension of disbelief was daunting, similar to Inception, or Justice is Mind.


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I'm obligated to last a few more hours.
Exact numbers and Jeffrey Epstein can kiss my ass.


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The Gods get pissed off rather easily.
Sensitive fuckers.


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Probably bullshit,

ex: how does the finally quiet from upstairs affect the serotonergic and dopaminergic systems?


AI Overview


The transition from a noisy environment to sudden quiet affects the serotonergic and dopaminergic systems primarily through the
cessation of a stressor, leading to a reduction in stress hormones and the promotion of a regenerative state.

Serotonergic System Effects
  • Reduced Stress Response: Chronic noise exposure is a significant stressor that can activate the body's stress systems, which in turn alters the serotonergic system. The sudden quiet from upstairs likely signals the end of this stressor, allowing stress hormone levels to decrease, which helps the serotonergic system return to a more balanced state.
  • Restoration of Balance: Serotonin acts as the brain's "steadying force," involved in mood, balance, and emotional regulation. The return to a quiet, less stressful environment allows the system to regain its normal function, promoting feelings of contentment and emotional stability.
  • Auditory Processing: The serotonergic system plays a role in how the brain processes sound. Hearing loss or chronic noise exposure can alter the density of serotonin fibers and the function of serotonin receptors in auditory regions. The return to quiet may help in restoring normal function in these auditory pathways.

Dopaminergic System Effects
  • Modulation of Dopamine Synthesis: Sound exposure has been shown to dynamically induce dopamine synthesis in specific auditory neurons; the louder the sound, the more the enzyme essential for making dopamine is present. When the noise stops, the level of this enzyme and subsequent dopamine release in these specific pathways likely decreases, as the system is no longer "fine-tuning" activity to the loud acoustic changes.
  • Prefrontal Cortex Function: Noise exposure can impair cognitive function in a manner dependent on the prefrontal cortex (PFC), a process linked to increased dopaminergic activity (turnover) in that region due to stress. The cessation of noise, and the accompanying reduction in stress, can alleviate this excessive dopamine activity in the PFC, thereby improving cognitive performance, focus, and attention.
  • Neurogenesis and Reward: Silence, in contrast to noise, has been shown to potentially lead to the production of new neurons (neurogenesis) in certain brain regions like the hippocampus, an effect that can be linked to overall brain health and potentially influenced by the dopaminergic reward system.
In summary, the transition to quiet likely acts as a stress-relieving event that allows both neurotransmitter systems to move from a state of heightened, stress-induced activity/plasticity back to a more homeostatic and regenerative balance, which contributes to overall well-being and improved cognitive function.


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shot by both sides


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Pythagorean marbles.

Am I alone in being alone? Police reference unintended.
No pun intended, either.


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