Stock Market Thread - ALL COMBINED
- Thread starter vinnie
- Start date
I thought this would fly after the conference call.
Go figure, great earnings and it drops :shrug:
No biggie, it will be back.
The market should be up today too, instead it's taking a shit. WTF is going on?
Bought EXAS today too at $8.35. There will be big news this afternoon and this will take off big or drop big. I'm gambling it takes off. Trading will be halted at 1pm so get in before that if you want to gamble along with me. :0008
I wonder how the market reacts to this news :0corn
Exact Sciences Reports Positive Results for Colorectal Cancer Screening TestLast update: 10/28/2010 1:00:01 PMData from Preliminary Study Meets Goals for Cancer Detection, Exceeds for Pre-Cancer Detection MADISON, Wis., Oct 28, 2010 (BUSINESS WIRE) -- Exact Sciences (EXAS) today presented data showing that its non-invasive Cologuard(TM) stool-based (sDNA) screening test detected 64 percent of colorectal pre-cancers and 85 percent of cancers. The study was conducted in collaboration with Mayo Clinic and examined more than 1,100 patient samples. Results were presented at the 2010 Special Conference for Colorectal Cancer: Biology to Therapy held by the American Association for Cancer Research in Philadelphia, PA. Colorectal cancer is the second leading cancer killer in the United States. It often is considered the most preventable, yet least prevented cancer. Colorectal cancer is highly treatable if found early, but 40 percent of adults age 50 and older have not been screened as recommended. "This is the first study of an sDNA test to show such promising results in detecting colorectal pre-cancer," said lead investigator David A. Ahlquist, M.D., Mayo Clinic, Rochester, Minn. "Colorectal cancer is a treatable disease if caught early, and this test shows great promise as a potential addition to other available screening tools." The latest American Cancer Society colorectal cancer screening guidelines include the sDNA form of testing as a recommended screening option. The Cologuard sDNA test works by detecting specific altered DNA sequences in cells that are shed into the stool from pre-cancerous or cancerous polyps. If a DNA abnormality is identified from a patient's sample, a colonoscopy is required to confirm the results. Findings from the more than 1,100-patient study showed that Cologuard detected 64 percent of adenomas, or polyps, greater than 1 centimeter (cm) and 85 percent of cancer, at a specificity of 88 percent. Polyps over 1 cm are considered the pre-cancers most likely to progress to cancer. Detection rates did not vary by patients' age or sex, or by cancer location. "We are excited about these encouraging results for Cologuard, which may offer an important step in the early detection of this terrible disease," said Kevin T. Conroy, president and chief executive of Exact Sciences. Cologuard is an investigational device and is not available for sale in the United States. The company plans to begin clinical trials next year. About the Study Exact Sciences' novel sDNA test approach incorporates direct capture from stool supernatant and QuARTS(TM) (Quantitative Allele-specific Real-time Target and Signal amplification) assay technology. This technology is designed to significantly increase analytic sensitivity compared to first generation sDNA assays. These data represent an early evaluation of Cologuard in large specificity, training and test sets of 1,187 stool samples from well-characterized patients with and without colorectal neoplasia. By using a combination of methylation, mutation, and hemoglobin markers, the test set and the training set combined achieved sensitivities of 85.3 percent for detection of colorectal cancer and 63.8 percent for adenomas greater than 1 cm at a specificity of 88 percent. Polyps greater than 1 cm are considered the pre-cancers most likely to progress to cancer. Detection rates did not vary by age, sex, or cancer site. This study successfully showed high sensitivity for the detection of colorectal cancer and is the first non-invasive test to show potential to detect pre-cancerous adenomas. There will be an investor call and webcast with additional details on this study today at 3:00 pm EDT. On the call, Dr. David Ahlquist and Dr. Graham Lidgard, chief scientific officer of Exact Sciences, will describe the results of the validation study, including details of both the training and test sets. The webcast will be available at . Domestic callers should dial 877-212-6082 and international callers should dial 707-287-9332. The access code for both domestic and international callers is 15683774. A replay of the conference call will be available at the company's website. The conference call, webcast and replay are open to all interested parties. About Colorectal Cancer Colorectal cancer is the second leading cancer killer in the United States. The National Cancer Institute estimates there will be about 142,000 new cases of colorectal cancer diagnosed in 2010 and that more than 51,000 people will die from colon and rectal cancer this year. The American Cancer Society recommends that all Americans start getting tested for the disease at age 50. However, many patients do not comply fully with current screening recommendations. In fact, 60 percent of patients today are diagnosed with colorectal cancer in the late stages, primarily because of poor screening compliance. Collaboration with Mayo Clinic In June 2009, Exact Sciences entered into a collaboration and license agreement with Mayo Clinic. Under the license agreement, Exact Sciences secured exclusive rights to intellectual property developed by David Ahlquist, M.D., Mayo Clinic. The licensed patents cover advances in sample processing, analytical testing and data analysis associated with non-invasive, stool-based DNA screening for colorectal cancer. As part of the agreement, Exact Sciences will make up-front, milestone and royalty payments to Mayo Clinic and Dr. Ahlquist, and will provide funding for future work in Dr. Ahlquist's lab. Exact Sciences and Mayo Clinic also entered into a broad research and development relationship with Dr. Ahlquist's laboratory. The relationship provides Exact Sciences with an experienced research and development team that is focused on the company's colorectal screening test. Exact Sciences retains exclusive rights to commercialize the breakthroughs that result from this collaboration. About Exact Sciences Exact Sciences is a molecular diagnostics company focused on colorectal cancer. The company has exclusive intellectual property protecting its non-invasive, molecular screening technology for the detection of colorectal cancer. Stool-based DNA (sDNA) technology is included in the colorectal cancer screening guidelines of the American Cancer Society and the U.S. Multi-Society Task Force on Colorectal Cancer. For more information, please visit the company's website at . Certain statements made in this press contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities and Exchange Act of 1934, as amended that are intended to be covered by the "safe harbor" created by those sections. Forward-looking statements, which are based on certain assumptions and describe our future plans, strategies and expectations, can generally be identified by the use of forward-looking terms such as "believe," "expect," "may," "will," "should," "could," "seek," "intend," "plan," "estimate," "anticipate" or other comparable terms. Forward-looking statements in this press release may address the following subjects among others: statements regarding the sufficiency of our capital resources, expected operating losses, expected license fee revenues, expected research and development expenses, expected general and administrative expenses and our expectations concerning our business strategy. Forward-looking statements involve inherent risks and uncertainties which could cause actual results to differ materially from those in the forward-looking statements, as a result of various factors including those risks and uncertainties described in the Risk Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10-K and our subsequently filed Quarterly Reports of Form 10-Q. We urge you to consider those risks and uncertainties in evaluating our forward-looking statements. We caution readers not to place undue reliance upon any such forward-looking statements, which speak only as of the date made. Except as otherwise required by the federal securities laws, we disclaim any obligation or undertaking to publicly release any updates or revisions to any forward-looking statement contained herein (or elsewhere) to reflect any change in our expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based. SOURCE: Exact Sciences
Exact Sciences Reports Positive Results for Colorectal Cancer Screening TestLast update: 10/28/2010 1:00:01 PMData from Preliminary Study Meets Goals for Cancer Detection, Exceeds for Pre-Cancer Detection MADISON, Wis., Oct 28, 2010 (BUSINESS WIRE) -- Exact Sciences (EXAS) today presented data showing that its non-invasive Cologuard(TM) stool-based (sDNA) screening test detected 64 percent of colorectal pre-cancers and 85 percent of cancers. The study was conducted in collaboration with Mayo Clinic and examined more than 1,100 patient samples. Results were presented at the 2010 Special Conference for Colorectal Cancer: Biology to Therapy held by the American Association for Cancer Research in Philadelphia, PA. Colorectal cancer is the second leading cancer killer in the United States. It often is considered the most preventable, yet least prevented cancer. Colorectal cancer is highly treatable if found early, but 40 percent of adults age 50 and older have not been screened as recommended. "This is the first study of an sDNA test to show such promising results in detecting colorectal pre-cancer," said lead investigator David A. Ahlquist, M.D., Mayo Clinic, Rochester, Minn. "Colorectal cancer is a treatable disease if caught early, and this test shows great promise as a potential addition to other available screening tools." The latest American Cancer Society colorectal cancer screening guidelines include the sDNA form of testing as a recommended screening option. The Cologuard sDNA test works by detecting specific altered DNA sequences in cells that are shed into the stool from pre-cancerous or cancerous polyps. If a DNA abnormality is identified from a patient's sample, a colonoscopy is required to confirm the results. Findings from the more than 1,100-patient study showed that Cologuard detected 64 percent of adenomas, or polyps, greater than 1 centimeter (cm) and 85 percent of cancer, at a specificity of 88 percent. Polyps over 1 cm are considered the pre-cancers most likely to progress to cancer. Detection rates did not vary by patients' age or sex, or by cancer location. "We are excited about these encouraging results for Cologuard, which may offer an important step in the early detection of this terrible disease," said Kevin T. Conroy, president and chief executive of Exact Sciences. Cologuard is an investigational device and is not available for sale in the United States. The company plans to begin clinical trials next year. About the Study Exact Sciences' novel sDNA test approach incorporates direct capture from stool supernatant and QuARTS(TM) (Quantitative Allele-specific Real-time Target and Signal amplification) assay technology. This technology is designed to significantly increase analytic sensitivity compared to first generation sDNA assays. These data represent an early evaluation of Cologuard in large specificity, training and test sets of 1,187 stool samples from well-characterized patients with and without colorectal neoplasia. By using a combination of methylation, mutation, and hemoglobin markers, the test set and the training set combined achieved sensitivities of 85.3 percent for detection of colorectal cancer and 63.8 percent for adenomas greater than 1 cm at a specificity of 88 percent. Polyps greater than 1 cm are considered the pre-cancers most likely to progress to cancer. Detection rates did not vary by age, sex, or cancer site. This study successfully showed high sensitivity for the detection of colorectal cancer and is the first non-invasive test to show potential to detect pre-cancerous adenomas. There will be an investor call and webcast with additional details on this study today at 3:00 pm EDT. On the call, Dr. David Ahlquist and Dr. Graham Lidgard, chief scientific officer of Exact Sciences, will describe the results of the validation study, including details of both the training and test sets. The webcast will be available at . Domestic callers should dial 877-212-6082 and international callers should dial 707-287-9332. The access code for both domestic and international callers is 15683774. A replay of the conference call will be available at the company's website. The conference call, webcast and replay are open to all interested parties. About Colorectal Cancer Colorectal cancer is the second leading cancer killer in the United States. The National Cancer Institute estimates there will be about 142,000 new cases of colorectal cancer diagnosed in 2010 and that more than 51,000 people will die from colon and rectal cancer this year. The American Cancer Society recommends that all Americans start getting tested for the disease at age 50. However, many patients do not comply fully with current screening recommendations. In fact, 60 percent of patients today are diagnosed with colorectal cancer in the late stages, primarily because of poor screening compliance. Collaboration with Mayo Clinic In June 2009, Exact Sciences entered into a collaboration and license agreement with Mayo Clinic. Under the license agreement, Exact Sciences secured exclusive rights to intellectual property developed by David Ahlquist, M.D., Mayo Clinic. The licensed patents cover advances in sample processing, analytical testing and data analysis associated with non-invasive, stool-based DNA screening for colorectal cancer. As part of the agreement, Exact Sciences will make up-front, milestone and royalty payments to Mayo Clinic and Dr. Ahlquist, and will provide funding for future work in Dr. Ahlquist's lab. Exact Sciences and Mayo Clinic also entered into a broad research and development relationship with Dr. Ahlquist's laboratory. The relationship provides Exact Sciences with an experienced research and development team that is focused on the company's colorectal screening test. Exact Sciences retains exclusive rights to commercialize the breakthroughs that result from this collaboration. About Exact Sciences Exact Sciences is a molecular diagnostics company focused on colorectal cancer. The company has exclusive intellectual property protecting its non-invasive, molecular screening technology for the detection of colorectal cancer. Stool-based DNA (sDNA) technology is included in the colorectal cancer screening guidelines of the American Cancer Society and the U.S. Multi-Society Task Force on Colorectal Cancer. For more information, please visit the company's website at . Certain statements made in this press contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities and Exchange Act of 1934, as amended that are intended to be covered by the "safe harbor" created by those sections. Forward-looking statements, which are based on certain assumptions and describe our future plans, strategies and expectations, can generally be identified by the use of forward-looking terms such as "believe," "expect," "may," "will," "should," "could," "seek," "intend," "plan," "estimate," "anticipate" or other comparable terms. Forward-looking statements in this press release may address the following subjects among others: statements regarding the sufficiency of our capital resources, expected operating losses, expected license fee revenues, expected research and development expenses, expected general and administrative expenses and our expectations concerning our business strategy. Forward-looking statements involve inherent risks and uncertainties which could cause actual results to differ materially from those in the forward-looking statements, as a result of various factors including those risks and uncertainties described in the Risk Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10-K and our subsequently filed Quarterly Reports of Form 10-Q. We urge you to consider those risks and uncertainties in evaluating our forward-looking statements. We caution readers not to place undue reliance upon any such forward-looking statements, which speak only as of the date made. Except as otherwise required by the federal securities laws, we disclaim any obligation or undertaking to publicly release any updates or revisions to any forward-looking statement contained herein (or elsewhere) to reflect any change in our expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based. SOURCE: Exact Sciences
--has been an odd year for stocks Jack.
Use to be if you did your homework or guessed right on earnings you got rewarded--not so anymore--strange times
TIPS (treasury inflation protected bonds) offered at "minus" interest rate couple days ago--some very fragile times we are in.
Use to be if you did your homework or guessed right on earnings you got rewarded--not so anymore--strange times
TIPS (treasury inflation protected bonds) offered at "minus" interest rate couple days ago--some very fragile times we are in.
EXAS I joined Jack an got SAME SLAP in face. Info led us to believe we were on right side. BOY what a opportunity under 7 bucks. When this news sinks in and folks understand it alone is a 1 billion in sale product. The co wlil get bought out.
I never did have it. I think dawgball had it :shrug:
Maybe I had it for a day or two. :shrug:
Too bad :mj07:
